diffuse parenchymal lung diseases interstitial lung disease
Conditions
Interventions
Randomization between transbronchial cryobiopsy (followed by surgical biopsy in
case of inconclusive results) versus immediate surgical biopsy.
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: interstitial lung disease based on HR-CT scan and a ILD-multidisciplinary discussion panel decides there is a need for lungbiopsy.
Exclusion criteria
Exclusion criteria: Inability and willingness to provide informed consent, Inability to comply with study protocol, Use of carbasalate calcium, clopidogrel, or other new anti-platelet therapy that cannot be stopped temporarily, Thrombocytopenia 50 mmHg), Diffusing capacity 35 * Hypoxemia, PaO2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (prolonged) need for chest tube drainage | — |
Secondary
| Measure | Time frame |
|---|---|
| complications, comprehensive complication index, in hospital stay, days with chest tube, pain and pain medication use, health related quality of life, diagnostic yield and diagnostic confidence per diagnostic strategy and procedure, patient preference and health care costs. | — |
Countries
Netherlands
Outcome results
None listed