Tinnitus pitch matching by residual inhibition and contrast gain control.

Tinnitus pitch matching by residual inhibition and contrast gain control. - Tinnitus pitch matching

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48700

Enrollment

Registered

2018-12-18

Start date

2020-10-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tinnitus

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Tinnitus group (A, n=20): - No reported neurological or psychiatric disorders (excluding tinnitus and hearing loss); - Chronic tinnitus (lasting more than 6 months); - Adult, 18-75 years of age; - Symmetric hearing loss with PTA (average threshold 1000-2000-4000 Hz) >= 30 dB; - Written informed consent; Hearing loss group (B, n=20): - No reported neurological or psychiatric disorders (excluding hearing loss); - Adult, 18-75 years of age; - Symmetric hearing loss with PTA (average threshold 1000-2000-4000 Hz) >= 30 dB; - Written informed consent; Control group (C, n=20) - Healthy subjects (i.e., excluding tinnitus, no medical, neurological, or psychiatric disorders); - Adult, 18-75 years of age; - Normal hearing thresholds or mild hearing loss (average threshold

Exclusion criteria

Exclusion criteria: - All subjects who cannot fully understand the experimental task. - Non-conformance to any of the inclusion criteria stated above.

Design outcomes

Primary

Measure	Time frame
Part I: The primary endpoint will be the tinnitus pitch on psychoacoustic responses. These include the following: - Difference between audio samples and automatic method for tinnitus characterization. - Relation between participants* RI function and tinnitus pitch. Part II: The primary endpoint of this part will be the difference in contrast gain control between tinnitus patients, hearing loss patients and controls. These include the following: - Relation between behavioral measures and EEG responses for the three groups. - Relation between tinnitus pitch and contrast gain control measures for tinnitus patients.	—

Measure

Time frame

Part I: The primary endpoint will be the tinnitus pitch on psychoacoustic responses. These include the following: - Difference between audio samples and automatic method for tinnitus characterization. - Relation between participants* RI function and tinnitus pitch. Part II: The primary endpoint of this part will be the difference in contrast gain control between tinnitus patients, hearing loss patients and controls. These include the following: - Relation between behavioral measures and EEG responses for the three groups. - Relation between tinnitus pitch and contrast gain control measures for tinnitus patients.

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Countries

Netherlands

Outcome results