hypoxie en hyperoxie bij prematuriteit neonatal hypoxia and hyperoxia
Conditions
Interventions
In order to study the effectiveness over a longer period of time of the A-FiO2
function of the ventilator, preterm infants will be set at random to either
continuous use of the A-FiO2 function or to
Sponsors
Academisch Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: * From day 7 of life after being born with a gestational age under 28 weeks * Desaturation lower than 86% at least 8 times per day and/or a structural need of supplemental oxygen > 25% * Written informed parental consent
Exclusion criteria
Exclusion criteria: * Major congenital anomalies * If the attending physician deems participation in the study is not in the best interest of the infant * No ventilator with A-FiO2 function available
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome variable will be the proportion of time for both control settings with SpO2 within the assigned saturation TR (90-95%), measured over a time period of a month. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will be the proportion of time being in hypoxemia or hyperoxemia, distribution of SpO2 between the different settings, and cumulative amount of oxygen administered over 28 days and at final study day. | — |
Countries
Netherlands
Outcome results
None listed