aggression regulation problems Reactive aggression
Conditions
Interventions
Participants are asked to self-regulate their amygdala signal, as represented
by a thermometer, in response to pictures of human faces that change from a
neutral expression to an angry one. A transf
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Dutch military personnel or veterans - Age 18-60 - The presence of impulsive aggression problems according to the criteria as described by Coccaro (2012) - Provide written informed consent
Exclusion criteria
Exclusion criteria: - Alcohol or drug abuse and/or dependence - A history of neurological disorders (e.g., Parkinson*s disease, CVA, multiple sclerosis) - Claustrophobia - The presence of a pacemaker or other metallic implant that might interfere with MRI acquisition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters of the proposed study are (i) the tolerability of the training procedure, as measured by a short self-report questionnaire, (ii) the degree to which self-regulation training is successful, measured by statistical analysis of the amygdala signal during feedback runs, and (iii) transfer of the training effects, measured by statistical analysis of the amygdala signal during transfer runs. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secundary study parameters of the proposed study are (i) the extent to which the neurofeedback procedure reduces symptoms related to impulsive aggression, as measured by five self-report questionnaries, and (ii) the extent to which functional connectivity between the amygdala and prefrontal cortex is increased as a result of the training procedure, as measured by functional connectivity analysis. | — |
Countries
Netherlands
Outcome results
None listed