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Biomarkers and cardiovascular risk in disease models of non-alcoholic fatty liver disease

Biomarkers and cardiovascular risk in disease models of non-alcoholic fatty liver disease - Cardiovascular risk in NAFLD

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON48654
Enrollment
85
Registered
2017-11-08
Start date
2018-05-25
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fatty liver nonalcoholic fatty liver disease (NAFLD)

Interventions

None listed

Sponsors

Medisch Universitair Ziekenhuis Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy individuals: - age >

Exclusion criteria

Exclusion criteria: - Contraindications for MRI (i.e. claustrophobia, heart pacemaker or other electronic devices implanted in the body, history of collapse or seizure, or pregnancies

Design outcomes

Primary

MeasureTime frame
a set of candidate biomarkers of DNL measured in plasma

Secondary

MeasureTime frame
Secondary outcome: endothelial function (reactive hyperaemia peripheral applanation tonometry, laser doppler flowmetry and plasma biomarkers) Other parameters: hepatic fat accumulation (magnetic resonance spectroscopy) and fat distribution (MRI)

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)