Activation of prefrontal cortex in elderly people from Okinawa in comparison to elderly from the Nederlands

Activation of prefrontal cortex in elderly people from Okinawa in comparison to elderly from the Nederlands - Brain activation in elderly from Okinawa

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48651

Enrollment

Registered

2019-04-03

Start date

2019-10-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognition Healthy ageing

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: aged between 65 and 80 years old

Exclusion criteria

Exclusion criteria: 1. Current diagnosis of psychiatric or neurological illness 2. MMSE

Design outcomes

Primary

Measure	Time frame
1. Differences in frontal brain activation (at equal or better performance levels) on a verbal fluency task compared between Okinawan and Dutch elderly. 2. Differences in frontal brain activation (at equal or better performance levels) on memory processing of meaningless shapes between Okinawan and Dutch elderly. 3. Differences in leftward lateralisation (as young people do) for brain activation during a verbal fluency task between Okinawan and Dutch elderly.	—

Measure

Time frame

1. Differences in frontal brain activation (at equal or better performance levels) on a verbal fluency task compared between Okinawan and Dutch elderly. 2. Differences in frontal brain activation (at equal or better performance levels) on memory processing of meaningless shapes between Okinawan and Dutch elderly. 3. Differences in leftward lateralisation (as young people do) for brain activation during a verbal fluency task between Okinawan and Dutch elderly.

—

Secondary

Measure	Time frame
Correlation of HbO levels and lateralization index with performance on cognitive tests, APOE4 gene variation, SFS scores and PASE scores .	—

Countries

Netherlands

Outcome results