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In utero sonographic assessment of calve muscles in fetuses with clubfeet (pes equinovares) and fetuses with no structural anomalies with follow-up after birth.

In utero sonographic assessment of calve muscles in fetuses with clubfeet (pes equinovares) and fetuses with no structural anomalies with follow-up after birth. - In utero sonographic assesement of calve muscles in fetuses.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON48647
Enrollment
70
Registered
2019-12-20
Start date
2020-04-08
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clubfeet Pes equinovares

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patient should be over the age of 18 years - Singleton pregnancy - All fetuses with unilateral or bilateral idiopathic pes equinovares referred to, or presenting at, Amsterdam UMC for targeted ultrasound examination around 20 weeks of gestation.

Exclusion criteria

Exclusion criteria: - Patients under 18 years - Twin pregnancy - Multiple congenital anomalies - An- or oligohydramnios - History of uterus anomalies - Septa in the uterine cavity during this pregnancy

Design outcomes

Primary

MeasureTime frame
The primary objective of the study is to examine muscle atrophy in fetuses with single or bilateral PEV, in comparison to a normal population by measuring the circumference of the upper and lower legs. The measurements will be performed prenatally at 20 weeks of gestation and around 28-30 weeks of gestation, neonates will be examined directly after birth and 6 weeks post-partum.

Secondary

MeasureTime frame
The length of the bones of the upper- and lower extremities and the length of the feet will be measured to examine if there is a difference in the length of the bones in fetuses affected with single or bilateral IPEV in comparison to the normal population.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)