Geen N/a
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Male gender Caucasian race Age 20-40 years BMI between 18 and 27.5 kg/m2 Non-smoking Steady dietary habits Generally healthy, no medication use that interferes with metabolism.
Exclusion criteria
Exclusion criteria: Cardiac problems and cardiovascular diseases, such as angina pectoris, cardiac infarction and arrhythmias Any medical condition requiring treatment and/or medication that might interfere with the investigated parameters. Unstable body weight (weight gain or loss >3kg in the past month) Participation in another biomedical study within 1 month prior to screening visit Participants, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician will be informed, cannot participate in this study Presence of Raynaud's phenomenon
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in thermal sensation as indicated by the maximal difference in finger temperature between the two ambient temperature conditions | — |
Secondary
| Measure | Time frame |
|---|---|
| energy expenditure heart rate blood pressure skin temperature core temperature sweat rate (only in experiment 2) | — |
Countries
Netherlands