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Validation of biomarkers for Crohn*s disease using peripheral blood cells of patients

Validation of biomarkers for Crohn*s disease using peripheral blood cells of patients - Validation of biomarkers for Crohn*s disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON48615
Enrollment
200
Registered
2019-01-04
Start date
2019-10-28
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

crohn's disease Inflammatory bowel disease ulcerative colitis

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients: - Provide informed consent - Within age 18 until 75 - Diagnosed with Crohn*s disease or ulcerative Colitis Healthy volunteers: - Provide informed consent - Within age 18 until 75 - Healthy, without a medical history of any inflammatory disease

Exclusion criteria

Exclusion criteria: -Patients: - Younger than 18 and older than 75 - Patients who cannot be properly informed about the risks due to an insufficient ability to speak Dutch or English - History of another inflammatory diseaseHealthy volunteer: - History of any inflammatory disease - Younger than 18 and older than 75 - Employees of the department of Gastroenterology - Family or friends of employees of the department of Gastroenterology

Design outcomes

Primary

MeasureTime frame
Definition of final staining panel which can allow for early inflammation dectection as well as distinguish between various forms of IBD , using peripheral blood samples.

Secondary

MeasureTime frame
1. Whether with this peripheral blood test a flare can be predicted 2. Whether this peripheral blood test can distinguish CD from UC patients. 3. To see how the medication of IBD patients can affect immune cell activation markers within peripheral blood.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)