monitoring van bloedsomloop tijdens anesthesie fluid changes during surgery
Conditions
Interventions
After induction of anaesthesia and once a steady state haemodynamic phase has
been reached before incision, all patients will be administered 5ml kg-1
crystalloids i.v. in 5-10 minutes. The haemodyn
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Patients scheduled for elective non-cardiac surgery requiring invasive arterial blood pressure monitoring. * Patients older than 18. * ASA physical status I-III. * Informed and willing to give written informed consent.
Exclusion criteria
Exclusion criteria: * Patients who refuse to participate. * Patients unable to consent (i.e. severe mental disorder, younger than 18). * Patients with pacemakers. * Patients with severe cardiac pathologies or hemodynamically unstable. * Patients with end-stage renal failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Raw COqCO data, which includes impedance variables, will be collected as a database and used for optimization and validation of the qCO algorithm Also, the absolute value of RPVI, as obtained by the Masimo Radical 7 monitor, and its fluid-induced change (*RPVI) will be assessed, in comparison to its clinical reference, SVV. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Comparison of the prediction of fluid responsiveness by RPVI with both FloTrac/EV1000-derived SVV and traditional PVI. - Ability of RPVI to predict fluid responsiveness, defined as an increase in CO > 15%, and comparing it with the ability of SVV to predict fluid responsiveness. - Ability of SpHb to track changes in Hb concentration following fluid administration by comparing it to reference (satellite-lab) Hb values. | — |
Countries
Netherlands
Outcome results
None listed