Oxidation-reduction potential in relation to vitamin C status in criticall ill patients

Oxidation-reduction potential in relation to vitamin C status in criticall ill patients - VitC-ORP

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48570

Enrollment

Registered

2018-11-29

Start date

2018-12-11

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ernstig zieke patienten opgenomen op de intensive care volwassenen Oxidative stress vitamin C status

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, all of the following criteria must be met: - * 18 years old; - Critically ill patients admitted to the ICU (SIRS/sepsis, trauma, post cardiac arrest); - Written informed (proxy) consent.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

Measure	Time frame
Plasma vitamin C concentration (µmol/l), oxidative stress parameter sORP and the anti-oxidant capacity (AOC)	—

Secondary

Measure	Time frame
Course of vitamin C concentration during the first days of ICU treatment. Relation between plasma vitamin C concentration and - Severity of illness and organ failure scores: o Acute Physiology and Chronic Health Evaluation, APACHE III and IV scores o Sequential organ failure assessment (SOFA) score - Clinical outcome measures.	—

Countries

Netherlands

Outcome results