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Treatments for auditory verbal hallucinations in patients with borderline personality disorder: Cognitive Behavioural Therapy for hearing voices (CBT) and treatment with Flupentixol

Treatments for auditory verbal hallucinations in patients with borderline personality disorder: Cognitive Behavioural Therapy for hearing voices (CBT) and treatment with Flupentixol - CBT and Flupentixol for AVH in BPD

Status
Unknown
Phases
Phase 4
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON48446
Enrollment
26
Registered
2019-10-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Auditieve verbale hallucinaties Borderline personality disorder Borderline. Auditory verbal hallucinations hearing voices

Interventions

None listed

Sponsors

Parnassia (Den Haag)
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age 18 years or older, BPD confirmed with the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID II), AVH occurring at least daily, and written informed consent for participation into this study from the patient.

Exclusion criteria

Exclusion criteria: Pregnancy and schizophrenia spectrum disorders, except for 1. Brief psychotic disorder with hallucinations, and 2. Other specific or nonspecific schizophrenia spectrum and other psychotic disorder in case of persistent auditory hallucinations.

Design outcomes

Primary

MeasureTime frame
Primary outcome measure: AVH-related items of the Psychotic Symptom Rating Scales.

Secondary

MeasureTime frame
Secondary outcome measures: Voice Power Differential scale (VPDS), Visual Analogue Scale (2 items severity malevolence and omnipotence of the voices), Korte Klachten Lijst, Brief State Paranoia checklist and the Sheehan Disability Scale. These data will be collected once a week during the baseline, intervention and follow-up period. Furthermore for CBT, the Beliefs About Voices Questionnaire (BAVQ) and the Social Comparison Rating Scale to voices (SCRS) will be looked at. In case of flupentixol treatment: Subjects Reaction to Antipsychotics will be assessed three times.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)