Spieropbouw na inspanning building muscle protein muscle protein synthesis
Conditions
Interventions
All subjects will perform a single bout of whole-body resistance-type exercise.
Subsequently, subjects will ingest a beverage containing 0, 25, or 100 g of
protein
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Males - Aged between 18-40 years - Healthy - 18.5 * BMI * 30 kg/m2
Exclusion criteria
Exclusion criteria: - Smoking - Sports/exercise > 4 sessions/week - Lactose intolerant or allergies to milk protein - A history of neuromuscular problems - Use of anticoagulation medication - Recent (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myofibrillar protein synthesis rates over the full assessment period (12 h) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Myofibrillar protein synthesis rates assessed over 3 periods (0-4, 4-8 and 8-12 hours) - 1-13C-phenylalanine incorporation into muscle protein - Plasma amino acid concentrations & enrichments - Plasma glucose & insulin concentrations - Whole-body protein metabolism (synthesis, breakdown, oxidation, balance) - Whole-body protein kinetics (total rate of appearance, rate of endogenous appearance, rate of exogenous appearance, rate of disappearance) | — |
Countries
Netherlands
Outcome results
None listed