Respiratoire klachten veroorzaakt door verschillende onderliggende ziektebeelden Respiratoiry complaints
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients (* 18 years) presenting in the ED with dyspnoea, respiratory rate > 20/min or peripheral oxygen saturation
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Not capable to give informed consent within reasonable time after stabilisation and abating of the accompanying psychological stress, and no representative available to give informed consent on behalf of the patient. - Arterial blood gas results are required for other reasons than determining the acid-base, ventilation and oxygenation status, such as determining the alveolar to arterial oxygen gradient (A-a gradient). - No physician or qualified nurse available for ABG sampling. - Failed ABG or VBG sampling after two attempts. - Previous participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is the frequency of alterations in treatment of patients with respiratory complaints in the emergency department (ED) based on venous blood gas (VBG) results compared to treatment based on arterial blood gas (ABG) results. We will assess which alterations in treatment occur, the characteristics of alterations and which ABG results cause the change. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are the agreement between venous and arterial pH, bicarbonate, pCO2, lactate and pO2 and the correlation between venous and arterial pO2 and the peripheral oxygen saturation measured with pulse oximetry. | — |
Countries
Netherlands