subfertiliteit reduced fertility Subfertility
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Maternal age >= 18 years - Singleton pregnancy - Naturally conceived or conceived after IVF or ICSI with or without pre-implantation genetic testing (PGT) - Good understanding of the Dutch language - BMI
Exclusion criteria
Exclusion criteria: - Pregnant via other ART-treatments such as ovulation induction (OI), intra-uterine insemination (IUI) or controlled ovarian hyperstimulation (COH) only.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoints are morphological placental characteristics such as placental calcifications, placental lakes and placental location, and vascular placental characteristics such as vascularisation index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are placenta biomarkers such as β-hCG, PAPP-A, PlGF and sFlt-1, foetal development, cell-free fetal DNA fraction in maternal plasma in NIPT and neonatal outcomes. | — |
Countries
Netherlands
Outcome results
None listed