Melanoma mole cancer
Conditions
Interventions
None listed
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. *18 years old 2. Histopathologically confirmed melanoma 3. Clinical stage IIIB/C/D, IV melanoma 4. Scheduled for a routine baseline [18F]-FDG PET/CT scan 5. Minimal one lesion with longest diameter * 20 mm 6. WHO performance status * 2 7. Ability to undergo the scan in supine position 8. Capacity to give informed consent
Exclusion criteria
Exclusion criteria: 1. Pregnant 2. Breast feeding 3. Claustrophobia 4. Confirmed diabetes mellitus I or II 5. Body weight >100 kg 6. Metal implants/prostheses, evaluated by study team 7. No systemic therapy (chemotherapy, immunotherapy, targeted therapy) 3 months prior to scan
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the variation in [18F]-FDG PET/CT quantification features between the test and retest scan. | — |
Secondary
| Measure | Time frame |
|---|---|
| Our secondary endpoints are the variation between post processing settings on the quantitative [18F]-FDG PET/CT features within scans. As quality control quantitative [18F]-FDG PET/CT features will also be measured on normal organ tissue. The amount of tumour lesions and their size will be measured. | — |
Countries
Netherlands
Outcome results
None listed