Non-osmotic sodium storage in placental tissue in hypertensive and normotensive pregnancies

Non-osmotic sodium storage in placental tissue in hypertensive and normotensive pregnancies - Non-osmotic sodium storage in placental tissue

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48312

Enrollment

150

Registered

2019-03-22

Start date

2019-06-28

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high blood pressure in pregnancy Hypertensive disorder of pregnancy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Pregnant women aged >= 18 years with a hypertensive disorder of pregnancy (pre-eclampsia, HELLP syndrome, gestational hypertension, chronic hypertension in pregnancy) - Gestational age between 28 weeks to 40 0/7 weeks; - Healthy subjects should be aged >= 18 years, normotensive during the whole pregnancy and matched for gestational age.

Exclusion criteria

Exclusion criteria: - Pregnant women aged

Design outcomes

Primary

Measure	Time frame
The chief parameter we will be studying is the difference in the amount of non-osmotic sodium storage in placental tissue, defined as sodium content per dry weight, between placentas of hypertensive pregnancies and normotensive pregnancies.	—

Secondary

Measure	Time frame
• The distribution of non-osmotic sodium storage in placental tissue; • The difference in GAG expression.	—

Countries

Netherlands

Outcome results