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Sleep neuroimaging: towards the neurobiology characterization of human REM sleep

Sleep neuroimaging: towards the neurobiology characterization of human REM sleep - REM sleep neuroimaging

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON48306
Enrollment
28
Registered
2020-07-15
Start date
2022-03-23
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neuroscientific research n.a

Interventions

None listed

Sponsors

Radboud Universiteit Nijmegen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 18 to 40 years old right handed

Exclusion criteria

Exclusion criteria: 1) Metal parts, that cannot be removed, are present in or on your upper body, e.g. plates, screws, aneurysm clips, metal splinters, piercings or medical plasters. Dental fillings, crowns, a metal wire behind the teeth, tattoos and contraceptive coils are allowed. The researcher will additionally inform you. 2) Clothing on the upper body containing any metal e.g. zips, buttons, hooks, braces, metal yarn (LUREX). This also applies to bras containing a metal brace wire. 3) You have an active implant, a pacemaker, insulin pump, neurostimulator and/or ossicle prosthesis. 4) You have a history of brain surgery. 5) You suffer from epilepsy. 6) You suffer from claustrophobia.

Design outcomes

Primary

MeasureTime frame
The main endpoints of this study are the blood level-dependent (BOLD) response and the EEG signal as dependent variables. We want to investigate brain connectivity on regions of interest for neurobiological models of dreaming such as the vmPFC, dlPFC, and hippocampus for instance. Brain networks during non-lucid, lucid REM sleep compared with wakefulness. Additionally, we are interested in EEG frequency characterization and regional activities during REM sleep.

Secondary

MeasureTime frame
Secondary aims of the proposed research include EEG correlates of lucid REM and non-lucid REM sleep, activity associated with tonic and phasic REM sleep that is theta, alpha, and gamma bands, REM saccades, and its activation association.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)