Hepatobiliary cancers liver- gallbladder and bileduct cancers liver disease, livercancer, gallbladdercancer, bileduct cancer
Conditions
Interventions
Per time point a maximum of 50 ml of peripheral blood will be prospectively
collected.
Sponsors
Erasmus Universiteit Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: HPB related malignancies, • Age >= 18 years of age • Diagnosed with HCC, CCA or GBC • Written informed consent, HPB related diseases, • Age >= 18 years of age • Diagnosed with viral hepatitis, cirrhosis, PSC, NAFLD or gallstones • Written informed consent, Healthy controls, • Age >= 18 years of age • No signs of relevant disease • Written informed consent
Exclusion criteria
Exclusion criteria: For all groups, • Females who are pregnant or breast-feeding. • History or other evidence of severe illness, other malignancy or any other condition which would make the patient, in the opinion of the investigators, unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of specific biomarkers for diagnosis and risk-prediction of HCC, GBC or CCA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
Netherlands
Contacts
Public ContactA Boonstra
Erasmus Universiteit Rotterdam
Outcome results
None listed