chronische ziekten met vermoeidheid en darmklachten chronic diseases
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Patients are diagnosed with chronic (immune) disorder; a chronic immune disease should be currently in remission/non active as determined by the GP (or medical specialist). 2. Report significant fatigue (score >
Exclusion criteria
Exclusion criteria: 1. Changes of medication or diet in the previous 3 months or during the course of the study, e.g., attending a weight loss program or changing to a vegetarian or vegan diet, or initiating new food supplements (including pro or prebiotics). 2. Current exacerbation of their chronic immune disease. 3. Excessive alcohol intake, defined as drinking more than 21 glasses of alcohol per week. 4. History of drug abuse or addiction. 5. Antibiotic use 6 months prior to the study. 6. Age below 18 or above 70 years. The upper limit of age is chosen since it is known that de immune system changes drastically above this age and this might affect the results of the study. 7. Pregnancy. 8. No access to internet and/or not using an iPhone or Android phone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This observational study will generate knowledge on the individual and across-subjects effectiveness of self-chosen products targeting the gut ecosystem on chronic fatigue. In addition, it will gather valuable data that can be analyzed further to test and generate new hypotheses on biological mechanisms in chronic fatigue (e.g., gut microbiota, barrier and immunological function). | — |
Secondary
| Measure | Time frame |
|---|---|
| The study will also collect data (via EMA diaries) about complaints that the patient determines individually (eg about sleepiness, mood, etc.). | — |
Countries
Netherlands
Outcome results
None listed