T cell respons in legionella

T cell respons in legionella - TRILO-study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48272

Enrollment

270

Registered

2019-04-04

Start date

2019-08-28

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Legionella disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: (group1) Hospitalized Patients with a proven Legionella infection (positive Legionella urine antigen test/ culture/ PCR) of which a subgroup willing to participate to the follow up study (group 2) healthy volunteers matched for age and gender (group 3) Patients with clinical presentations of pneumonia and a proven other pathogen

Exclusion criteria

Exclusion criteria: • immunosuppressive medication •

Design outcomes

Primary

Measure	Time frame
Diagnostic potential of the elispot to identify Legionella disease patients	—

Secondary

Measure	Time frame
To evaluate the T-cell respons in time in patients with a Legionella infection	—

Countries

Netherlands

Outcome results