BMI dependent regulation of macrophages and monocytes in pregnancy

BMI dependent regulation of macrophages and monocytes in pregnancy - BMI, macrophages and pregnancy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48238

Enrollment

Registered

2019-06-03

Start date

2019-09-27

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

being fat Obesity

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - written informed consent - 18-40 years - BMI >30 or BMI >19 -

Exclusion criteria

Exclusion criteria: smoking - immune related disorders - fever / illness within the last month - fertility treatment (ovulation induction, intra-uterine insemination, IVF-ICSI) - BMI

Design outcomes

Primary

Measure	Time frame
Primary parameters will be the effects of maternal BMI on levels of macrophage cell and monocyte subsets in decidual tissue and maternal blood.	—

Secondary

Measure	Time frame
Secondary parameters will be the differences in the effect of maternal blood stimulation with conditioned medium of adipose tissue and LPS and differences in monocyte subsets in umbilical cord blood.	—

Countries

Netherlands

Outcome results