adult-onset diabetes type 2 diabetes
Conditions
Interventions
A 3-week time restricted feeding (TRF) intervention will be compared with a
3-week control arm. During TRF, subjects will only be allowed to eat within a
ten-hour time frame during the day. Subjects
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Well-controlled, non-insulin treated type 2 diabetes, males and postmenopausal females, age: 50 - 75, BMI: >25 kg/m2, habitual eating times spread over a time period of 14 hours
Exclusion criteria
Exclusion criteria: Not being able to adhere to a restricted feeding schedule, use of medication that interferes with the study outcomes as determined by the dependent physician, extreme early bird or extreme night person, any medical condition that will preclude the safe performance of the measurements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study endpoint is the effect of time restricted feeding on morning (fasted) hepatic glycogen content, measured with 13C-Magnetic Resonance Spectrometry (MRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| The main secondary outcome is the effect of TRF on insulin sensitivity, measured with the hyperinsulinemic 2-step clamp. | — |
Countries
Netherlands
Outcome results
None listed