larynx- pharynx cancer throat cancer
Conditions
Interventions
Application of the radioactive tracer:
In patients who have given permission to take part in the project the H&N
doctor will carry out an inspection of the tumor with the flexible scope such
as is r
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -male or female aged > 18 years -mucosal tumor of the oropharynx, hypopharynx or larynx -patients planned to undergo biopsy via flexible endoscopy -patients planned to undergo curative radiotherapy with or without concurrent chemotherapy -patient provided written informed consent
Exclusion criteria
Exclusion criteria: -patients who underwent previous surgery or radiotherapy to the neck -patients with airway obstruction causing stridor -prior allergic reaction to Tc-99m-nanocolloid -pregnancy -unable to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A SPECT image of sufficient quality for localization of the sentinel node(s). This is a qualitative endpoint and is assessed by consensus between a nuclear medicine physician (A. Arens), head and neck surgeons (J. Honings, R. Takes, W. Weijs) and a radiation oncologist (J. Kaanders). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Is it feasible to administer at least 2 injections during the same procedure? 2. Can sentinel nodes identified by SPECT be recognized on routine CT or MRI? | — |
Countries
Netherlands
Outcome results
None listed