Clinical implications of asymptomatic corneal shedding of herpes simplex virus

Clinical implications of asymptomatic corneal shedding of herpes simplex virus - CORSURV

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48221

Enrollment

Registered

2020-01-15

Start date

2020-07-20

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

herpetic keratitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Age * 18 years. - Informed consent. - Immunecompetent individual. - Positive HSV-1 infection status - No symptomatic ocular HSV-1 disease during 3 months preceding first study sampling. - No anti-HSV therapy during 1 month preceding first study sampling. - No immunesuppressive drugs during the 3 months preceding first study sampling. - No previous keratoplasty

Exclusion criteria

Exclusion criteria: - Individual not able to adhere to bi-daily oral and corneal sampling for 30 consecutive days. - Individuals wearing contact lenses

Design outcomes

Primary

Measure	Time frame
Main study parameters/endpoints: Proportion of HSV-1 DNA positive oral and corneal samples.	—

Countries

Netherlands

Outcome results