The long-term effects of Small Vessel Disease

The long-term effects of Small Vessel Disease - The long-term effects of Small Vessel Disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48199

Enrollment

250

Registered

2019-07-01

Start date

2019-09-24

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral vasculopathy - White matter hyperintensities

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Participants alive of the RUN DMC cohort (cohort of patients with small vessel disease) • In such a condition allowing to visit the research centre • Written informed consent

Exclusion criteria

Exclusion criteria: - (Psychiatric) disease interfering with cognitive testing or follow-up - Contra-indications to MR Imaging

Design outcomes

Primary

Measure	Time frame
The SVD neuroimaging markers, incidence of vascular events, dementia and parkinsonism.	—

Secondary

Measure	Time frame
- Change in cognitive function - Severity of BBB dysfunction, based on quantitative pharmacokinetic parameter values	—

Countries

Netherlands

Outcome results