hypertentie blood pressure Pharmacokinetics
Conditions
Interventions
12 weeks of educational intervention with intense (weekly) personalized
monitoring and feedback focusing on nitrate rich vegetables (intervention
group), dietary nitrate supplementation (supplementa
Sponsors
Hogeschool van Arnhem en Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Elevated blood pressure or stage 1 hypertension: Elevated blood pressure. Elevated blood pressure is a systolic pressure ranging from 120 to 129 mm Hg and a diastolic pressure below 80 mm Hg. Elevated blood pressure tends to get worse over time unless steps are taken to control blood pressure. Stage 1 hypertension. Stage 1 hypertension is a systolic pressure ranging from 130 to 139 mm Hg or a diastolic pressure ranging from 80 to 89 mm Hg. - Current vegetable intake
Exclusion criteria
Exclusion criteria: - Use of medication (with known vasoactive properties); - Currently smoking - Currently supplementing diet with nitrate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main aim of the current study is to investigate the effect of a 12 week dietary intervention focusing on increasing vegetable intake on 24h blood pressure. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Plasma concentrations: plasma nitrate and nitrate, plasma cholesterol, HDL, LDL, triglyceride, troponin I; - Dietary intake: total macro- and micronutrient intake, vegetable and dietary nitrate intake; - Blood pressure and heart rate - Submaximal aerobic endurance exercise | — |
Countries
Netherlands
Outcome results
None listed