Focused fMRI and Brainstem Evoked Response Audiometry (BERA) to Probe the Brainstem Mechanism in Tinnitus

Focused fMRI and Brainstem Evoked Response Audiometry (BERA) to Probe the Brainstem Mechanism in Tinnitus - Focused fMRI and BERA for tinnitus

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48145

Enrollment

Registered

2019-08-12

Start date

2020-03-10

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ringing in the ears

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: To be eligible to participate in this study, the subject - must be in the age range of 18-80 years old. - must have a hearing threshold of both ears between 40 dB and 60 dB, if he/she is in one of the bilateral hearing loss groups. - must have a hearing threshold between 40 dB and 60 dB for one ear, and the normal hearing threshold, less than 20 dB, for the other ear, if he/she is in one of the unilateral hearing loss groups. - must have a hearing threshold of less than 20 dB for both ears, if he/she is in one of the normal threshold groups.

Exclusion criteria

Exclusion criteria: - Non-conformance to any of the inclusion criteria. - Contraindication for MRI according to the MRI checklist. - Reported medical, neurological, or psychiatric disorders (excluding tinnitus and hearing loss).

Design outcomes

Primary

Measure	Time frame
The main endpoints are differences between response characteristics associated with hearing loss laterality and the presence of tinnitus. These differences include the difference in the response amplitudes of various brainstem nuclei as assessed by fMRI, BERA and, tonotopic maps as assessed by MRI.	—

Secondary

Measure	Time frame
n.v.t	—

Countries

Netherlands

Outcome results