chronic inflammation of the bowel Inflammatory Bowel Disease
Conditions
Interventions
None listed
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1. Patients who are suspected of having or diagnosed with VEO-IBD regardless of race, ethnicity, and gender will be included 2. Diagnosis of IBD (Crohn disease and ulcerative colitis) is based on regular endoscopy, histology, intestinal MRI, video capsule endoscopy or a combination of these (IBD Working Group ESPGHAN, 2014) 3. Both parents of the identified patients will be asked to participate, in order to perform segregation analysis, linkage analysis, or association studies 4. Written informed consent (parents and children (in case of age >12 years)
Exclusion criteria
Exclusion criteria: 1. Any patient perceived by the clinical team to be at risk for complications if collection of biospecimens samples for research purposes are taken (e.g., excessive bleeding) 2. No fetal specimens will be taken from pregnant women for prenatal genetic testing 3. No Approved and signed informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To detect potential disease-causing mutations and subsequently create possible novel targeted treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Geen | — |
Countries
Netherlands
Outcome results
None listed