The neural correlates of age-related variability in word learning: a neuroimaging study of maturation effects on word learning

The neural correlates of age-related variability in word learning: a neuroimaging study of maturation effects on word learning - Variability in word learning

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48125

Enrollment

240

Registered

2021-03-16

Start date

2021-09-17

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None, this research will be conducted with healthy participants to investigate word learning. brain research human cognition

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Healthy children, adolescents and adults between 8 and 30 years of age -Normal/ corrected to normal vision -Normal hearing -Willingness and ability to understand the nature and content of the study

Exclusion criteria

Exclusion criteria: -History of neurological or psychiatric treatment -History of brain surgery or epilepsy -Any current psychological diagnosis according to the DSM criteria -Any acute or chronic neurological disorders -Pregnancy -MRI incompatability (metal parts in upper body, implants, medical devices or medial plasters) -Claustrophobia

Design outcomes

Primary

Measure	Time frame
In the proposed study, the main study parameters are the brain activation patterns of two fMRI tasks that probe language learning. The main outcomes of this study are the age-related differences in the neural correlates of language learning i.e. functional MRI BOLD activity. We will relate those neural responses to behavioural word learning & artificial language learning success.	—

Secondary

Measure	Time frame
In addition to the primary study parameters/outcomes, we will relate the maturational status of the participants* brain to both the activation patterns of the fMRI tasks and the behavioural assessments examining language and cognitive abilities. Maturation of the brain will be assessed using measures of white matter integrity, such as fractional anisotropy, as well as indices reflecting cortical structure, such as cortical thickness. The behavioral assessments will include variables like first and second language proficiency in vocabulary and more general language related abilities like verbal fluency.	—

Measure

Time frame

In addition to the primary study parameters/outcomes, we will relate the maturational status of the participants* brain to both the activation patterns of the fMRI tasks and the behavioural assessments examining language and cognitive abilities. Maturation of the brain will be assessed using measures of white matter integrity, such as fractional anisotropy, as well as indices reflecting cortical structure, such as cortical thickness. The behavioral assessments will include variables like first and second language proficiency in vocabulary and more general language related abilities like verbal fluency.

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Countries

Netherlands

Outcome results