NATURAL KILLER CELL PHENOTYPE IN UNEXPLAINED RECURRENT MISCARRIAGES

NATURAL KILLER CELL PHENOTYPE IN UNEXPLAINED RECURRENT MISCARRIAGES - OVIDE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48099

Enrollment

126

Registered

2019-02-28

Start date

2019-04-16

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Miscarriage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: We will include non-pregnant women between the age of 18 and 36. Group 1: *cases* Recurrent (>2) unexplained miscarriages, defined by normal parental karyotype, no maternal thrombophilia and no uterine abnormality. Group 2: *controls* Previous uncomplicated pregnancy, defined by healthy live birth after 37 weeks of gestation without major obstetric complications.

Exclusion criteria

Exclusion criteria: - Current or recent (

Design outcomes

Primary

Measure	Time frame
Percentage of NK cells with an activating phenotype in peripheral blood.	—

Secondary

Measure	Time frame
- Percentage of NK cells with an activating phenotype in menstrual blood - VO2 max: measured in millilitres per kilogramme of body weight per minute - Lifestyle questionnaire: Simple Lifestyle Indicator Questionnaire (SLIQ) score - Total body water: fat free mass in kilogramme of body weight	—

Countries

Netherlands

Outcome results