veroudering aging senescence
Conditions
Interventions
None listed
Sponsors
Centrum voor Bewegingswetenschappen, Sector F
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: The young subjects will be between 20 and 30 years old, whereas the old subjects will be 65+ years old. All the participants will be generally healthy and able to walk without an assistive aid (i.e. walker, cane).
Exclusion criteria
Exclusion criteria: Mini Mental State Examination score 180/115), previous stroke, Parkinson's disease, Alzheimer's disease or other forms of dementia, treatment of cancer within the last three months, severe asthma or chronic bronchitis, musculoskeletal disorders that disables a person from normal walking, joint replacement or a fracture present in one of the lower extremities, severe diabetes with neuropathy, visual impairments that disables normal mobility, BMI > 30 kg/m2, pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average muscle activity (in mV) of uniarticular leg extensor muscles (i.e. gluteus maximus, vastus lateralis, vastus medialis, soleus) during positive and negative joint work separately. | — |
Secondary
| Measure | Time frame |
|---|---|
| Average muscle activity (in mV) of biarticular leg muscles (i.e. biceps femoris, semitendinosus, rectus femoris, gastrocnemius medialis) and uniarticular leg flexor muscles (i.e. tibialis anterior) during positive and negative joint work separately. Time duration of muscle activity (in ms) of leg flexor and extensor muscles during positive and negative joint work separately. Joint kinetics during gait: - Negative joint work (hip, knee, ankle) (in J/kg/m) - Positive joint work (hip, knee, ankle) (in J/kg/m) Subject anthropometrics: - Body height - Body weight | — |
Countries
Netherlands
Outcome results
None listed