The effect of prolonged and repeated moderate-intensity exercise on inflammation in patients with Inflammatory Bowel Disease.

The effect of prolonged and repeated moderate-intensity exercise on inflammation in patients with Inflammatory Bowel Disease. - IB4D study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48058

Enrollment

Registered

2019-06-19

Start date

2019-07-14

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic inflammation of the colon inflammatory bowel disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - 18 years of age or older (all participants) - Diagnosis of Crohn*s disease or ulcerative colitis (total or left-sided colitis) made by gastroenterologist (IBD participants) - Participation in Nijmegen Four Day Marches, edition 2019 (all participants)

Exclusion criteria

Exclusion criteria: - Use of biologicals (e.g. infliximab, adalimumab, golumimab, ustekinumab) (IBD participants) - History of IBD or other gastro-intestinal diseases such as celiac disease or Irritable Bowel Syndrome (IBS) (healthy participants) - History of significant systemic diseases, such as diabetes mellitus, cancer, cardiovascular or respiratory disease, that may have an effect on study outcomes (healthy participants)

Design outcomes

Primary

Measure	Time frame
The main study parameter is the change in gastrointestinal inflammation measured by faecal calprotectin in the IBD subjects.	—

Secondary

Measure	Time frame
Secondary parameters are inflammatory markers in blood and clinical disease activity measured by Harvey Bradshaw Index (HBI) in Crohn*s Disease and the Simple Clinical Colitis Activity Index (SCCAI) in ulcerative colitis.	—

Countries

Netherlands

Outcome results