Long term vascular and psychosocial complications in adolescent and young adult survivors of head and neck cancer treated with radiotherapy.

Long term vascular and psychosocial complications in adolescent and young adult survivors of head and neck cancer treated with radiotherapy. - Late Effects Head and Neck Cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48049

Enrollment

Registered

2019-11-25

Start date

2020-01-22

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vascular toxicity

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients treated with unilateral radiotherapy of the neck at adolescent or young adult age (18-40 year) 5-10 years before. - Competent to make own discicions - *18 years of age

Exclusion criteria

Exclusion criteria: - Contra indication MRI - Not able to understand the Dutch language

Design outcomes

Primary

Measure	Time frame
1. Vascular complications: a. Intima Media thickness on ultrasonography in the irradiated versus the non-irradiated artery b. Carotid wall elastography on ultrasonography in the irradiated versus the non-irradiated artery c. Carotid wall thickness on MRI in the irradiated versus the non-irradiated artery d. Radiological characteristics of carotid wall changes on MRI of the irradiated versus the non-irradiated artery e. Cerebral infarctions and white matter lesions on MRI f. Cardiovascular risk profile 5-10 years after radiotherapy because of HNC	—

Measure

Time frame

1. Vascular complications: a. Intima Media thickness on ultrasonography in the irradiated versus the non-irradiated artery b. Carotid wall elastography on ultrasonography in the irradiated versus the non-irradiated artery c. Carotid wall thickness on MRI in the irradiated versus the non-irradiated artery d. Radiological characteristics of carotid wall changes on MRI of the irradiated versus the non-irradiated artery e. Cerebral infarctions and white matter lesions on MRI f. Cardiovascular risk profile 5-10 years after radiotherapy because of HNC

—

Secondary

Measure	Time frame
2. Psychosocial complications: a. Cognitive function 5-10 years after RT in HNC patients b. Frequency of memory complaints, anxciety, depression, fatique c. Employment ability	—

Countries

Netherlands

Outcome results