The effects of a healthy lifestyle on brain vascular function in elderly people

The effects of a healthy lifestyle on brain vascular function in elderly people - Lifestyle and Brain Vascular Function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON48037

Enrollment

Registered

2019-12-19

Start date

2020-01-22

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulin Resistance Syndrome Metabolic Syndrome Syndrome X

Interventions

The intervention group will follow a 16-week healthy lifestyle intervention, which includes physical activity according to the dutch guidelines and dietary advice adhering to the guidelines describe

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Aged between 55-70 years - BMI between 25-35 kg/m2 (overweight and slightly obese) - Sedentary (assessed as low physically active using the International Physical Activity Questionnaire) - Rights handedness and footedness - Fasting plasma glucose

Exclusion criteria

Exclusion criteria: - Current smoker, or smoking cessation

Design outcomes

Primary

Measure	Time frame
At baseline and follow-up, participants have to attend the research facilities for one day to perform measurements. The primary endpoint is the effect of a 16-week healthy lifestyle intervention on cerebral blood flow, as assessed by Arterial Spin Labeling.	—

Secondary

Measure	Time frame
Cognitive performance and HOMA-ir	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)