digestion/absorption muscle growth
Conditions
Interventions
39g milkprotein or 100g cheese (10 per group)
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Healthy males Age between 18 and 35 y inclusive BMI between 18.5 and 30 kg/m2
Exclusion criteria
Exclusion criteria: * Allergies to milk proteins * Lactose intolerant * Smoking * Phenylketonuria * Diabetes Mellitus * Diagnosed GI tract disorders or diseases * Arthritic conditions * A history of neuromuscular problems * Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). * Use of certain anticoagulants (use of thrombocyte aggregation inhibitors such as acetylsalicylic acid and carbasalaatcalcium is permitted. Use of other thrombocyte aggregation inhibitors will be discussed with the responsible physician) * Blood donation within 2 months of study initiation * Hypertension (according to WHO criteria) * Recent participation in amino acid tracer studies (less than 1 year ago)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is the fractional synthetic rate (FSR) of mixed muscle protein post-prandial (0 - 240 min) period. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fractional synthetic rate of the basal (-150 - 0 min) period. Total plasma amino acids Plasma glucose and insulin Whole-body protein kinetics | — |
Countries
Netherlands
Outcome results
None listed