Pathogenic role of virus-specific T-cells in corneas of patients with herpetic stromal keratitis (HSKPATH)

Pathogenic role of virus-specific T-cells in corneas of patients with herpetic stromal keratitis (HSKPATH) - HSKPATH

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47972

Enrollment

Registered

2020-01-21

Start date

2019-12-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

herpetic keratitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >= 18 years. Immunecompetent individual. Positive HSV-1 infected Documented ocular disease history for at least 1 year. Indication for therapeutic corneal transplantation*

Exclusion criteria

Exclusion criteria: Individuals with documented HIV, HBV or HCV infection. Individuals on immune therapy or did so in the past 3 months.

Design outcomes

Primary

Measure	Time frame
Characteristics of HSV-specific T-cells in diseased cornea tissue specimens of HSK and non-HSK patients.	—

Secondary

Measure	Time frame
None	—

Countries

Netherlands

Outcome results