Anabolic Resistance Muscle anabolism Muscle growth
Conditions
Interventions
300g quark
resistance exercise
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Healthy males * Age between 18 and 35 y or 65 and 85 y inclusive * BMI between 18.5 and 30 kg/m2
Exclusion criteria
Exclusion criteria: * Allergies to milk proteins * Lactose intolerant * Smoking * Phenylketonuria * Diabetes Mellitus (diagnosed, or fasting glucose >7.0 mmol/L, or HbA1c >6.5) * Diagnosed GI tract disorders or diseases * Arthritic conditions * A history of neuromuscular problems * Any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications). * Use of certain anticoagulants (use of thrombocyte aggregation inhibitors such as acetylsalicylic acid and carbasalaatcalcium is permitted. Use of other thrombocyte aggregation inhibitors will be discussed with the responsible physician) * Blood donation within 2 months of study initiation * Hypertension (according to WHO criteria; >90/140 mmHg) * Recent participation in amino acid tracer studies (less than 1 year ago) * Physical activity (not training more than 3 times per week and no structured resistance training.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in postprandial muscle protein synthesis in rest and after exercise compared to rested postabsorptive muscle protein synthesis | — |
Secondary
| Measure | Time frame |
|---|---|
| whole body protein metabolism plasma amino acids plasma glucose and insulin. | — |
Countries
Netherlands
Outcome results
None listed