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Stress Resilience and the Brain in Burnout

Stress Resilience and the Brain in Burnout - STRAIN-BO

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON47939
Enrollment
90
Registered
2020-05-13
Start date
2020-10-06
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burnout work related stress

Interventions

None listed

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Age 18-55 years * Native Dutch speakers * Right-handed * Normal or corrected to normal vision * For females: Free cycling, - Additionally, patients will need to have received a diagnosis from HSK clinics characterized as unidentified somatoform disorder, adjustment disorder (DSM-V) or from AMDumc with a diagnosis of burnout.

Exclusion criteria

Exclusion criteria: *General exclusion criteria for fMRI: Metal implants or splinters, surgical clips, prostheses, artificial heart valves, claustrophobia, electronic equipment in body (such as a pacemaker), preg-nancy, and epilepsy. Furthermore, a potential subject who meets any of the following criteria will be excluded from participation in this study:, * Psychiatric: o Current major depression, or ADHD o Lifetime history of bipolar disorder, schizophrenia, delusional disorder, schizoaffective disorder, schizophreniform disorder or other psychotic disorders o Schizoid or schizotypal personality disorder o Current alcohol- or substance dependence o Mental retardation (IQ

Design outcomes

Primary

MeasureTime frame
The primary study outcome will be the stress reactivity difference in the brain between people with burnout and controls, and the relationship of this response to daily life stress reactivity and glucocorticoid dysfunction.

Secondary

MeasureTime frame
The effects of childhood trauma on glucocorticoid dysfunction on burnout will be examined.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)