To test the use of a Microdialysate Automated Collection Device for cortisol sampling and to assure reproducibility in the LUMC of data reported by others

To test the use of a Microdialysate Automated Collection Device for cortisol sampling and to assure reproducibility in the LUMC of data reported by others - To test the use of a Microdialysate Automated Collection Device

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47911

Enrollment

Registered

2018-10-22

Start date

2018-08-07

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

onderzoek heeft in eerste instantie betrekking op normale fysiologische situatie, in tweede instantie patienten met bijnierinsufficientie adrenal insufficiency healthy people physiological situation

Interventions

Cortisol

Microdialysis

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: First: Healthy adult males or females, aged between 20-60 years Only if insufficient data, also adults with adrenal insufficiency, males or females, aged between 20-60 years

Exclusion criteria

Exclusion criteria: Pregnancy, Allergy to local anaesthetic, hydrocortisone replacement therapy or any known abnormalities to the HPA axis (the latter only in case of healthy persons, first step of the protocol).

Design outcomes

Primary

Measure	Time frame
- Peripheral tissue cortisol profiles/day rhythms - Reproducibility results reported by other groups	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)