The effect of intravenous lidocaine to prevent intracranial pressure increase in endotracheal intubation assessed by optic nerve sheath diameter

The effect of intravenous lidocaine to prevent intracranial pressure increase in endotracheal intubation assessed by optic nerve sheath diameter - Effect of lidocaine on ICP increase in endotracheal intubation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON47899

Enrollment

Registered

2018-08-10

Start date

2018-10-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain pressure Intracranial pressure

Interventions

lidocaine 1,5 mg/kg iv or placebo

Endotracheal intubation

Intracranial pressure

Lidocaine

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patients aged >18 year old, scheduled for elective surgery under general anesthesia with a planned duration of the procedure > 30 min that can be routinely performed with a ETI.

Exclusion criteria

Exclusion criteria: - Surgery of the eye an eye region - Neurosurgical procedure and neurosurgical procedure in the past - Neurological disorders - Bilateral eye trauma - Glaucoma - Mentally retarded patients - Contraindications for the use of lidocaine e.g.

Design outcomes

Primary

Measure	Time frame
Difference in optic nerve sheet diameter in millimetre before, during and after intubation between both groups.	—

Secondary

Measure	Time frame
Time taken for the ONSD to return back to its initial value once the patients is intubated.	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)