alertheid alertness
Conditions
Interventions
Intervention comprises of:
1) placebo + dim light
2) placebo + bright light
3) melatonin + dim light
4) melatonin + bright light
The light conditions are simulated with the use of a Philips Energ
Alertness
Light
Melatonin
Time of day
Sponsors
Rijksuniversiteit Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Age between 20-30 - Healthy - Dutch speaking - Women have to use hormonal contraceptives
Exclusion criteria
Exclusion criteria: - Diagnosed color blindness (ishihara's color blindness test) - Use of photosensitizing medication or sleep medication - Drug use - Moderate to high levels of caffeine intake during a day (5 or more cups) - Smokers - Diabetic disease - Shift work schedule in the 3 months prior to participation - Travel over 2 or more time zones in 1 month prior to participation - Epworth Sleepiness Scale >18 - PSQI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is subjective alertness measured by the Karolinska Sleepiness Scale (KSS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters are objective alertness, measured by physiological correlates: pupillary parameters and skin temperature. In addition, indirect parameters, measured through the auditory reaction time task, are used. | — |
Countries
The Netherlands
Outcome results
None listed