Autosomal Dominant Polycystic Kidney Disease or polycystic kidney disease polycystic kidney disease
Conditions
Interventions
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of ADPKD, based upon the modified Ravine criteria or documented by treating nephrologist or internist. 2. Age 18 years and older. 3. Providing informed consent.
Exclusion criteria
Exclusion criteria: • Patients, who are unlikely to adequately comply with the trial*s procedures (due for instance to medical condition likely to require an extended interruption or discontinuation) • Patients taking medications or having concomitant illnesses that are likely to influence the natural course of ADPKD (e.g. nephrotoxic medications such as chronic NSAID, cyclosporine, lithium and immunosuppressant use, and e.g. diabetes mellitus and patients with proteinuria > 1 g/24hr). • Patients, who receive renal function replacement therapy • Pregnancy at moment of inclusion • Patients with a life expectancy less than 1 year at moment of inclusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate disease progression factors and association of disease biomarkers with the onset and severity of ADPKD-related outcomes like hypertension, renal function, renal pain renal, albuminuria, renal urine concentrating ability, hematuria, cyst infection, nephrolithiasis and others. | — |
Secondary
| Measure | Time frame |
|---|---|
| To summarize the levels of self-estimated health status, pain, QoL, ADPKD-related health burden, health care resource use. | — |
Countries
Netherlands
Contacts
Public ContactT Bais
Universitair Medisch Centrum Groningen
Outcome results
None listed