The effects of magnesium salts on vascular stiffness: a long-term study in healthy overweight and slightly obese men and women.

The effects of magnesium salts on vascular stiffness: a long-term study in healthy overweight and slightly obese men and women. - Magnesium salts and vascular stiffness

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON47872

Enrollment

162

Registered

2018-04-23

Start date

2018-03-27

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

'Vascular stiffness' en 'Stiffness of the blood vessels'

Interventions

After the first test day, the overweight and slightly obese subjects will be randomly assigned to magnesium citrate, magnesium sulphate, magnesium oxide or to placebo for 24 weeks. Subjects assigned

Intervention study

Magnesium

Vascular stiffness

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Aged between 45-75 years - Women postmenopausal: two or more years after last menstruation - Body mass index between 25-35 kg/m2 (overweight and slightly obese)

Exclusion criteria

Exclusion criteria: - High habitual dietary magnesium intake - Plasma glucose * 7.0 mmol/L - Serum total cholesterol * 8.0 mmol/L - Serum triacylglycerol * 4.5 mmol/L - Current smoker, or smoking cessation

Design outcomes

Primary

Measure	Time frame
- Vascular stiffness	—

Secondary

Measure	Time frame
- Blood pressure - Gut microbiote - Urine, plasma and intracellular magnesium Markers of: - Vascular function - Inflammation - Vascular activity	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)