Dancing-eyes-and-feet syndrome Opsoclonus Myoclonus Syndrome
Conditions
Interventions
Long term sequelae
Opsoclonus Myoclonus Syndrome
Treatment outcomes
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: All patients with OMS, diagnosed and treated at the Sophia Children*s Hospital will be included. OMS is defined as the presence of *3 of the following symptoms: [1] opsoclonus, [2] myoclonus and/or ataxia, [3] behavioural change and/or sleep disturbance and [4] neuroblastoma. Age-matched children with pilocytic astrocytoma, diagnosed and treated at the Sophia Children*s Hospital will be included.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: - Insufficient command of the Dutch language (spoken and/or written) - Age above 12 years Children with pilocytic astrocytoma will be excluded from participation, when they were treated with radiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study will have multiple endpoints: * Computer-assisted assessments: - Eye tracking: smooth pursuit and saccades; - Balance plate: scatter in center-of-gravity; | — |
Secondary
| Measure | Time frame |
|---|---|
| * Clinical endpoints - OMS rating scale score; - SARA-score. * Computer-assisted assessments: - Score *Shelby*s Quest*. * Questionnaires; | — |
Countries
The Netherlands
Outcome results
None listed