Epilepsie epilepsy excessive daytime sleepiness idiopathic hypersomnia Narcolepsy
Conditions
Interventions
None listed
Sponsors
Stichting Epilepsie Instellingen Nederland
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Subjects are > 18 years Diagnosed in one of the below mentioned categories: 1. Epileptic patients with seizures only during the night for at least the last year 2. Epileptic patients with seizures only during the day for at least the last year 3. Type 1 narcolepsy patients 4. Type 2 narcolepsy patients 5. Idiopathic hypersomnia 6. Healthy controls
Exclusion criteria
Exclusion criteria: - Color vision deficiency - Recent (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| As the primary endpoint, responsiveness to light will be measured using the pupillometer, measuring the diameter of the pupil while exposed to no light, red light and blue light, resulting in the Post-illumination Pupillary Response (PIPR) (Van der Meijden et al., 2015). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are vigilance as measured by the SART (total error score Van Schie et al., 2012) and the ESS. In addition, we will assess habitual sleep timing from the MCTQ, fatigue with the FSS and sleep quality from the PSQI. | — |
Countries
Netherlands
Outcome results
None listed