ESTABLISHING THE DIAGNOSTIC AND PROGNOSTIC ROLE OF NARROW BAND IMAGING IN HEAD AND NECK CANCER

ESTABLISHING THE DIAGNOSTIC AND PROGNOSTIC ROLE OF NARROW BAND IMAGING IN HEAD AND NECK CANCER - NBI in HNC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47793

Enrollment

450

Registered

2015-08-20

Start date

2015-09-10

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck cancer HNSCC

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - suspicion of or proven carcinoma of the oral cavity, nasal cavity, pharynx or larynx. - suspicion of a benign lesion of the larynx - > 18 yrs of age - informed consent

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
Primary Objective: to validate NBI (using flexible and rigid laryngosopes) in HNC as a prognosticator and establish NBI as a reliable diagnostic tool by discriminating (pre)malignant lesions from benign lesions	—

Secondary

Measure	Time frame
1. To identify NBI + WLI as superior to WLI alone in the early detection of local HNC recurrences after first line treatment 2. To identify NBI + WLI as a better diagnostic and staging tool in the determination of tumor field and as a consquence tumor staging than WLI alone 3. To conclude that inter-observer and intra-observer variability/reliability in the visual analysis of benign and (pre) malignant lesions in the upper aerodigestive tract is higher using NBI+WLI than WLI alone. 4. To increase reliability and decrease inter-/intra-observer variability by creating a NBI-atlas which will be helpful in correct interpretation of NBI.	—

Measure

Time frame

1. To identify NBI + WLI as superior to WLI alone in the early detection of local HNC recurrences after first line treatment 2. To identify NBI + WLI as a better diagnostic and staging tool in the determination of tumor field and as a consquence tumor staging than WLI alone 3. To conclude that inter-observer and intra-observer variability/reliability in the visual analysis of benign and (pre) malignant lesions in the upper aerodigestive tract is higher using NBI+WLI than WLI alone. 4. To increase reliability and decrease inter-/intra-observer variability by creating a NBI-atlas which will be helpful in correct interpretation of NBI.

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Countries

Netherlands

Outcome results