cognitive function decline of mental functions
Conditions
Interventions
In part 2 of the study the participants in the experimental group participate
in the COACH program, a lifestyle training developed to increase daily physical
activity. The COACH method consists of 7
Sponsors
Vrije Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age * 55 years - Males and females - Able to perform the Timed Up & Go Test with or without assistive device - Mini Mental State Examination (Folstein, Folstein, & McHugh, 1975) score higher than 25 - In the second part of the study only those participants who display low levels of physical activity as measured in Part 1 of the study are recruited and included
Exclusion criteria
Exclusion criteria: - Weelchair-bound - diagnosed with dementia or mild cognitive impairment - diagnosed with a neurodegenerative disease - diagnosed with a progressive or terminal disease - diagnosed with serious cardiovascular disease, such as heart failure that limit physical activity - epilepsy - (history of) substance abuse - (history of) major psychiatric illness (e.g. depression) - severe visual or auditory problems - insufficient proficiency of the Dutch language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main outcome measure is cognitive function, measured with neuropsychological tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are physical functioning measured with performance-based field tests, IGF-1 and BDNF serum levels, blood metabolite concentrations and ADLS, mood and quality of life, measured by questionnaire. | — |
Countries
Netherlands
Outcome results
None listed