Predictive markers for individualized biology-driven treatment for esophageal cancer

Predictive markers for individualized biology-driven treatment for esophageal cancer - Predictive markers in esophageal cancer treatment

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON47729

Enrollment

180

Registered

2013-05-22

Start date

2013-07-09

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer esophageal carcinomas

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients with esophageal cancer that undergo endoscopic ultrasound for disease stageing.

Exclusion criteria

Exclusion criteria: Patients with PT-INR/PTT >1.5

Design outcomes

Primary

Measure	Time frame
Study the relationship between genome-wide genetic and epigenetic alterations as well as characteristics of the tumor immune microenvironment of esophageal carcinomas and the association with disease free and progression free survival in order to identify biomarkers for response to treatment.	—

Secondary

Measure	Time frame
Study the relationship between genome-wide genetic and epigenetic alterations as well as characteristics of the tumor immune microenvironment of in esophageal carcinomas and the association to prognosis. Thereby we hope to identify a molecular alteration or profile that is associated with a high risk of distant metastasis.	—

Countries

Netherlands

Outcome results