Freezing of gait in Parkinson's Disease
Conditions
Interventions
EEG data analysis
Freezing of Gait
Parkinson's Disease
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: * Men/women of age > 18 years with idiopathic Parkinson*s disease, as diagnosed by the UK Brain Bank Criteria. * Written informed consent. * Presence of FOG (defined as a score of 1 on question 1 "Have you experienced FOG in the past month" from the NFOGQ). * Disabling/regular FOG (defined as a score of 3 "Very often, more than one time a day" on question 2 "How often do you experience FOG" from the NFOGQ).
Exclusion criteria
Exclusion criteria: * Comorbidities that cause severe gait impairment (e.g. severe arthrosis or neuropathy). * Severe cognitive impairments (MMSE
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The following study parameters will be collected during the 1st and 2nd experiments. Both experiments will be video-taped and rated for the presence of FOG. The videos only can be accessed by researchers. o 64- and 32-channel EEG data will be acquired by ActiCap and TMSi EEG system from participants in both two experiments, respectively; o Gait parameters such as cadence will be calculated from 4 accelerometers on lower body of participants (TMSi, 4 sensors = 2 above ankles, 2 above knees); o Gait parameters related to the gait of upper body will be calculated from 2 accelerometers and 2 EMG sensors (TMSi) above metacarpophalangeal joints and forearms of participants, respectively ; o ECG data measured (TMSi); o Vertical forces of foot acquired by TMSi Footswitches. | — |
Secondary
| Measure | Time frame |
|---|---|
| no applicable | — |
Countries
The Netherlands
Outcome results
None listed